Although I personally prefer the freedom of self-syndication, I would be remiss in not providing information for those who actually want to go the national syndication route. The following is a list of the top name, and not so top name cartoon syndicates in North America.
I suggest that if you want to submit to the national syndicates, that you do your homework first to understand just what it is they want to get from you. Where possible, I have provided a direct link to the syndicates that have web pages of information as to how to submit your cartoon features to them. For those without links, write a letter requesting submission guidelines, and follow it to the letter. You gotta play the game their way if you want to play at all.
Note: this listing is not a recommendation of the newspaper companies or how they will respond to your cartoons.
Cartoonists & Writers Syndicate
1923 Wickham Road
New York, NY 10024
Creators Syndicate
5777 W. Century Boulevard, Suite 700
Los Angeles, CA 90045
Comics they distribute: Momma, B.C., The Wizard of Id,
Contact person: Anita Tobias
Submission instructions
Chronicle Features
870 Market Street
Suite 1011
San Francisco, CA 94102
King
Features Syndicate
235 East 45th Street
New York, NY 10017
Comic they distribute: Mama's Boyz, Blondie, Hagar the Horrible, Family
Circus, Beetle Bailey
Contact person: Jay Kennedy
Los Angeles Times Syndicate
218 S. Spring Street
Los Angeles, CA 90012
Comics they distribute: Dr. Katz, Love Is
Contact person: Cathy Irvine
Tribune
Media Services
435 North Michigan Avenue, Suite 1500
Chicago, IL 60611
Comics they distribute: Herb & Jamaal, Mother Goose and Grimm, Shoe,
Dick Tracy
Contact person: Mark Mathes
Submission
instructions
United
Media
200 Madison Avenue
New York, NY 10016
Comics the distribute: Jumpstart,Peanuts, Dilbert, Drabble
Contact person: Amy Lago
United Cartoonist Syndicate
PO Box 7081
Corpus Christi, TX 78415
Universal Press Syndicate
4520 Main Street
Kansas City, MO. 64111
Comics they distribute: Where I'm Coming From,Garfield, Cathy, Doonesbury,
For Better or for Worse
Contact person: Lee Salem
Submission
instructions
Information source: Graphic Artists Guild Handbook Pricing & Ethical Guidelines 9th edition